“中国制造2025”背景下“班组长型”人才培养的挑战与应对

"班组长型"人才正是实现"中国制造2025"宏伟蓝图的基层驱动力量之一,"班组长型"人才的培养是当前相关职业院校重要任务,分析了"中国制造2025"对当前高职教育的新挑战以及对企业班组长的新要求,并提出了"中国制造2025"背景下"班组长型"人才培养的应对措施。     

超细全尾砂充填体动态力学特性研究

充填体作为人工矿柱,为矿房回采创造了条件,但经常受到爆破等冲击荷载作用。充填体的动态力学特性直接关系到充填采矿法的安全高效实施。通过单轴压缩试验和分离式霍布金森压杆(Split Hobkinson Pressure Bar,SHPB)试验技术,进行了不同充填配比参数的超细全尾砂充填体压缩试验,得到其静载和动载下的应力-应变曲线和能量变化曲线,并分析了其破坏模式。研究表明:充填体质量浓度越高,灰砂比越大,峰值应力和峰值应变随之增大,呈现正相关性,其中灰砂比和质量浓度对应力的影响相对一致,但应变受质量浓度影响更大;当冲击荷载由0.3 MPa增大至0.6 MPa时,充填体的破坏形式由保持完整形态变为产生裂纹,直至被压碎,转变为完全失稳破坏状态;充填体能量吸收随着冲击荷载的增加而逐渐递增,但质量浓度和灰砂比增大时,充填体比能量和能量吸收率反而下降,其中灰砂比是影响充填体吸能效率的主要因素,质量浓度次之。     

药用辅料对CYP3A活性的影响及其对仿制药质量和疗效一致性评价的指导作用

药物制剂的处方和工艺是保证药物质量和疗效的基础，药用辅料是药物制剂处方的重要组成部分。部分药用辅料可影响CYP3A的活性，继而可能影响其底物在体内的代谢和生物利用度。在中国和美国，相对生物利用度是仿制药研究的关键内容。我国正在推进仿制药质量和疗效一致性评价。因此，了解药用辅料对CYP3A的影响及其对一致性评价的指导作用具有十分重要的现实意义。     

Context enabled decision aids to support the situation awareness and performance of risk engineers carrying out loss prevention surveys

Routine inspection by insurance companies at their clients’ facility, also known as loss prevention survey, help identify the best strategies to minimize damages when there is a high-speed wind event. More specifically, wind vulnerabilities associated with a building are evaluated using a process known as windstorm risk inspection. This routine inspection helps clients reduce the extent of damages caused by high-speed wind events including hurricane and tornado. Risk engineers make use of their subjective and analytical deduction skills to successfully carry out the inspection tasks. In this research the researchers investigated the effect of context-based visualization strategies on situation awareness and their understanding of the situation. The study examined how different types of information contribute towards the three levels of situation awareness. Following a between-subjects study design, 65 participants completed the study. Each session lasted 90–120 min. A checklist based and predictive display-based decision aids were tested and found to be effective in supporting the situation awareness requirements as well as performance of risk engineers. However, the predictive display only helped with certain tasks such as understanding the interaction among different components on the rooftop. For remaining tasks such as perceiving obvious issues like membrane tear, clogged drains and vegetation growth, checklist alone was sufficient. This study helped the understanding of the advantages and disadvantages of the decision aids tested. More specifically, these decision aids can improve the mental model of novice risk engineers. Additionally, this study provided insights that could help design training materials for infrastructure inspectors.     

折臂式随车起重机转台的拓扑优化设计

为了使折臂式随车起重机转台在最大应力不超过材料许用应力的前提下实现轻量化设计的目的,通过ADAMS软件仿真确定其极限工况,对转台进行静力学分析及拓扑优化。通过拓扑优化得到了理想的材料分布。基于优化结果调整转台结构,并对改进后的转台进行静力学分析。结果表明,优化后的转台能够满足实际的使用需求。同时,转台质量降低了12%,证明了优化设计的有效性和可行性,并为折臂式随车起重机的相关设计提供了一定的借鉴。     

Purification and characterization of a novel bacteriocin CAMT2 produced by Bacillus amyloliquefaciens isolated from marine fish Epinephelus areolatus

A novel bacteriocin named CAMT2 was produced by strain ZJHD3-06 which was isolated from the marine fish Epinephelus areolatus and identified as Bacillus amyloliquefaciens, Bacteriocin CAMT2 inhibits important food spoilage and food-borne pathogens such as Listeria monocytogenes, Staphylococcus aureus, Escherichia coli and Vibrio parahaemolyticus. Bacteriocin CAMT2 was purified by ammonium sulfate precipitation, gel filtration chromatography on Sephadex G-50 and reversed phase chromatography on a C₁₈ column. The molecular mass of the purified bacteriocin CAMT2 was about 20.0 kDa and N-terminal sequencing of the peptides revealed low similarity with existing antimicrobial peptides, as determined by an LC–MS/MS system. Bacteriocin CAMT2 was resistant for up to 100 °C and pH ranging 2–10, but lost its activity when treated with protease K. The bacteriocin also showed significant antimicrobial activity against L. monocytogenes in a meat model system. These obtained results suggest that bacteriocin CAMT2 has potential for use as a food biopreservative.     

电动汽车的双向DC-DC变换器多模态控制方法

针对当前电动汽车功率控制过程中存在负载跳变抗干扰性能差、响应速度较慢等问题,提出一种应用于电动汽车的双向DC-DC变换器多模态控制方法。文章详细分析了电动汽车双向DC-DC变换器的拓扑结构和升降压控制模式;结合不同工况下的变换器工作状态,分析电压和电流模式控制,得出其电压、电流开闭环函数;利用多模态控制方法,由变换器的功能控制单元下达电压、电流环给定信号来实现功率波动平抑控制;在MATLAB中搭建了仿真模型。仿真结果表明,文章所提出的控制方法能够较好地实现双向DC-DC变换器的功率波动平抑功能,具有稳定性好、对负载跳变抗干扰性能强、响应速度快的特点。     

A Pattern Recognition Method of Personalized Adaptive Learning in Online Education

Mobile Networks and Applications - In order to effectively identify the pattern of personalized adaptive learning in online education and improve the recommendation satisfaction of personalized...     

Hydroxyapatite forming ability,ion release and antibacterial activity of the melt-derived SiO2–P2O5–Na2O–CaO–F glasses modified by replacing CaO with SrO and ZnO

Since the discovery of 1970s, bioactive glass has been a hot topic of research because of its excellent biological activity, which makes it a material that can repair and replace human bone tissue organs. In this work, the bioactive glasses in the system SiO₂–P₂O₅–Na₂O–CaO–F with different amounts of strontium oxide (SrO) and zinc oxide (ZnO) were prepared by the conventional melt quenching technology. The hydroxyapatite (HA) forming ability, ion release and antibacterial activity of these prepared glasses were investigated and the obtained results illustrated that SrO-doped samples had a better ability to form HA in modified simulated body fluid (MSBF) than ZnO-doped samples. As the immersion time of the sample in MSBF increased, the content of HA phase gradually increased. In the same immersion time, the formation ability of HA and the variation of SrO substitution amount showed a non-linear trend, which is mainly related to the influence of SrO content on the glass network structure. The results of ion concentration showed that the formation of HA was the result of the comprehensive action of various ions in the solution, especially the release rate of Si⁴⁺ ions, which had a direct impact on the formation ability of HA. The antibacterial test illustrated that the difference in antibacterial activity of bacteria solution at different sample concentrations may be related to the high pH environment and the osmotic effects caused by the non-physiological concentration of ions in the solution. The glass sample contained 4 wt% SrO showed the minimum bactericidal concentration at 64 mg/mL. The glass samples prepared in this experiment had good biological activity and antibacterial effect, making them suitable for using in dentistry and orthopedic applications, as well as providing a valuable composition reference for the preparation of bioactive glass with excellent comprehensive properties.     

A comparison of manual handling risks in different domestic waste collection systems using three separate evaluation methods

Arising out of the challenge for Local Authorities (LAs) to operate sustainable systems of work, is to avoid the creation of ill-health including the most significant causes of physical absence, musculoskeletal disorders (MSDs).The study's aim was to compare the reliability of the manual handling element of the Health and Safety Executives (HSEs) risk comparator tool for different domestic waste collection methods with self-reported pain via body-mapping and MSD ill health absence rates. Participatory body-mapping exercises were carried out in five LAs with one LA resurveyed, six months after the move from 35 and 50 L containers to a wheeled bin recycling service.The lowest levels of self-reported pain were for services designed with 240l wheeled bins excluding glass; the highest levels were for services that included 100l of garden waste sacks and recycling boxes. Industry data supports previous laboratory studies showing wheeled bins to be associated with less MSD outcomes than boxes, baskets and sacks.Triangulation of data established a statistically significant correlation of 0.85 (Pearson) between average pain-count (APC) and the mean MSD absence rates, with a strong correlation of 0.77 (Spearman) between APC and risk rating. The correlation is moderate, 0.49 (Spearman) between MSD absence and risk rating, reflecting possible intervening variables and a low participation rate by LAs.The contribution of this study is to improve the design of sustainable waste collection strategies to minimise MSD associated absence. In the absence of reliable absence data, body mapping should be used as a proxy method of assessing MSD risk.